NR4A1

Across TCGA patient cohorts, NR4A1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,246 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NR4A1-associated genes across cancer lineages are NVL, CHKB-DT, and NXT2. Each is linked with NR4A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NR4A1-to-partner and partner-to-NR4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR4A1 versus NVL in PDAC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR4A1→partner) and Y-score (partner→NR4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NVL →	-0.455	-1.547	<.001	<.001	3	3
LUAD	CHKB-DT →	-0.499	-0.849	<.001	.001	3	3
UCEC	NXT2 →	-0.812	-0.984	.009	.003	3	2
UCEC	BUB3 →	-0.601	-0.612	.001	.005	3	2
PDAC	PDIK1L →	-0.491	-0.929	.009	.004	3	2
UCEC	SNRPCP20 →	+0.764	+0.971	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,246 associations by consensus.

NR4A1 vs NVL — PDAC

Explore this scatter interactively →