NR3C2

Across TCGA patient cohorts, NR3C2 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,161 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NR3C2-associated proteins across cancer lineages are APPL1, RPL5, and RPS2. Each is linked with NR3C2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NR3C2-to-partner and partner-to-NR3C2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR3C2 versus APPL1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR3C2→partner) and Y-score (partner→NR3C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APPL1 →	+0.295	+0.917	<.001	<.001	3	7
CCRCC	RPL5 →	-0.258	-0.804	<.001	<.001	3	7
CCRCC	RPS2 →	-0.313	-0.904	<.001	<.001	3	7
HNSC	SLC3A2 →	-0.573	-0.980	.001	<.001	3	7
GBM	SPTBN1 →	+0.366	+0.912	<.001	<.001	3	7
LUAD	UTP15 →	-0.357	-1.227	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,161 associations by consensus.

NR3C2 vs APPL1 — BRCA

Explore this scatter interactively →