NR3C1

Across TCGA patient cohorts, NR3C1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,467 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NR3C1-associated genes across cancer lineages are RPL7P21, LRRK2, and GGTA1. Each is linked with NR3C1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NR3C1-to-partner and partner-to-NR3C1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR3C1 versus RPL7P21 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR3C1→partner) and Y-score (partner→NR3C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPL7P21 →	+0.667	+0.311	<.001	<.001	3	6
UCEC	LRRK2 →	+1.076	+0.547	<.001	<.001	3	5
COAD	GGTA1 →	+1.128	+0.678	.002	.004	3	5
COAD	GIMAP1 →	+0.570	+0.574	.001	.001	3	5
UCEC	PECAM1 →	+0.655	+0.527	<.001	<.001	3	5
UCEC	BTK →	+1.016	+0.510	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,467 associations by consensus.

NR3C1 vs RPL7P21 — HNSC

Explore this scatter interactively →