NR3C1

Across TCGA cell cohorts, NR3C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,152 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NR3C1-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Cellular response to environmental stimulus, and Cellular response to abiotic stimulus. Each is linked with NR3C1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NR3C1-to-partner and partner-to-NR3C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by NR3C1-low versus NR3C1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR3C1→partner) and Y-score (partner→NR3C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.219	+1.820	<.001	<.001	3	13
SKIN	Cellular response to environmental stimulus →	+0.037	+0.792	<.001	<.001	3	13
SKIN	Cellular response to abiotic stimulus →	+0.037	+0.792	<.001	<.001	3	13
LIVER	Negative regulation of cilium assembly →	+0.084	+1.511	<.001	.001	3	12
LUNG_NSCLC_LUSC	Elastin metabolic process →	+0.279	+1.661	.001	.004	2	13
STOMACH	Positive regulation of supramolecular fiber organization →	+0.100	+2.801	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,152 associations by consensus.

Positive regulation of focal adhesion assembly by NR3C1 expression — BONE

Explore this box plot interactively →