NR2F6

Across TCGA cell cohorts, NR2F6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,075 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NR2F6-associated GO terms across cancer lineages are Mitochondrial calcium ion transmembrane transport, Negative regulation of osteoclast proliferation, and Fatty acid catabolic process. Each is linked with NR2F6 in more than 8 cancer types. Because this analysis shows association rather than direction, both NR2F6-to-partner and partner-to-NR2F6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial calcium ion transmembrane transport grouped by NR2F6-low versus NR2F6-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2F6→partner) and Y-score (partner→NR2F6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mitochondrial calcium ion transmembrane transport →	+0.113	+0.758	<.001	<.001	3	9
OVARY	Negative regulation of osteoclast proliferation →	-1.062	-0.994	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.112	+1.075	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.072	+0.864	.004	.001	3	9
SOFT_TISSUE	Negative regulation of NLRP3 inflammasome complex assembly →	+0.103	+1.058	<.001	<.001	3	9
BONE	Peptidyl-methionine modification →	+0.268	+1.330	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,075 associations by consensus.

Mitochondrial calcium ion transmembrane transport by NR2F6 expression — LARGE_INTESTINE

Explore this box plot interactively →