Across TCGA patient cohorts, NR2F2 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR2F2-associated genes across cancer lineages are ATM, PCNA, and PDCD4. Each is linked with NR2F2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NR2F2-to-partner and partner-to-NR2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2F2→partner) and Y-score (partner→NR2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.560	-3.087	.002	<.001	3	3
UCEC	PCNA →	+0.220	+1.906	.011	.016	3	2
UCEC	PDCD4 →	-0.429	-2.312	.023	.034	3	2
UCEC	ASNS →	+0.425	+1.807	.003	.025	3	2
UCEC	eIF4E →	+0.196	+1.906	.020	.016	3	1
UCEC	FoxM1 →	+0.276	+1.906	.007	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

NR2F2 survival (RNA) · tumor vs normal (RNA) · all NR2F2 data types