NR2F2

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NR2F2 mutation is significantly associated with the drug of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NR2F2-associated genes across cancer lineages are OSU-03012, CAP-232, and Embelin. Each is linked with NR2F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NR2F2-to-partner and partner-to-NR2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2F2→partner) and Y-score (partner→NR2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOSU-03012 →+0.401+2.889.001.02531
BLOOD_LeukemiaCAP-232 →+0.397+2.922.009.02421
BLOOD_LeukemiaEmbelin →+0.447+3.055.012.01911
BLOOD_LeukemiaXMD15-27 →+0.323+2.929.030.02411
BLOOD_LeukemiaCMK →+0.384+2.889.030.02511
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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