NR2E3

Across TCGA patient cohorts, NR2E3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,323 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NR2E3-associated proteins across cancer lineages are SRGAP3_S858, THSD4, and BIN3. Each is linked with NR2E3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NR2E3-to-partner and partner-to-NR2E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR2E3 versus SRGAP3_S858 in LSCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2E3→partner) and Y-score (partner→NR2E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRGAP3_S858 →	+0.695	+0.308	<.001	<.001	3	4
UCEC	THSD4 →	+1.469	+1.974	<.001	<.001	3	4
BRCA	BIN3 →	+0.452	+0.592	<.001	<.001	3	3
UCEC	RALGAPB →	+0.241	+1.085	<.001	.002	3	3
BRCA	RASAL2_S830 →	-0.623	-0.836	<.001	<.001	3	3
UCEC	CWC25_S337 →	-0.378	-1.243	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,323 associations by consensus.

NR2E3 vs SRGAP3_S858 — LSCC

Explore this scatter interactively →