NR2E3

Across TCGA cell cohorts, NR2E3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,317 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible NR2E3-associated GO terms across cancer lineages are mRNA 5'-splice site recognition, Cellular response to heat, and Regulation of protein export from nucleus. Each is linked with NR2E3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NR2E3-to-partner and partner-to-NR2E3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 5'-splice site recognition grouped by NR2E3-low versus NR2E3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2E3→partner) and Y-score (partner→NR2E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	mRNA 5'-splice site recognition →	+0.129	+0.333	.001	.007	3	6
SKIN	Cellular response to heat →	+0.089	+0.187	<.001	.009	3	5
SKIN	Regulation of protein export from nucleus →	+0.065	+0.125	<.001	.001	3	5
LIVER	Positive regulation of cytoskeleton organization →	+0.087	+0.128	.004	.005	3	5
LARGE_INTESTINE	Calcium export from the mitochondrion →	+0.105	+0.187	<.001	<.001	3	5
LIVER	Centrosome localization →	+0.091	+0.090	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,317 associations by consensus.

mRNA 5'-splice site recognition by NR2E3 expression — KIDNEY

Explore this box plot interactively →