NR2E1

Across TCGA cell cohorts, NR2E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 947 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible NR2E1-associated GO terms across cancer lineages are Positive regulation of translation, RNA splicing, via transesterification reactions, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with NR2E1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NR2E1-to-partner and partner-to-NR2E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by NR2E1-low versus NR2E1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2E1→partner) and Y-score (partner→NR2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of translation →	+0.050	+0.172	<.001	.008	3	6
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.076	+1.183	.005	.003	3	6
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.076	+1.183	.005	.003	3	6
OESOPHAGUS	mRNA splicing, via spliceosome →	+0.076	+1.183	.005	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Nuclear chromosome segregation →	+0.083	+0.435	.004	<.001	3	6
OESOPHAGUS	Negative regulation of blood-brain barrier permeability →	-0.254	-0.893	.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 947 associations by consensus.

Positive regulation of translation by NR2E1 expression — OVARY

Explore this box plot interactively →