NR2C2

Across TCGA patient cohorts, NR2C2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,085 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NR2C2-associated proteins across cancer lineages are TOP2B, DHX9, and GATAD2B. Each is linked with NR2C2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NR2C2-to-partner and partner-to-NR2C2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR2C2 versus TOP2B in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2C2→partner) and Y-score (partner→NR2C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.412	+0.375	<.001	<.001	3	7
GBM	DHX9 →	+0.241	+0.315	<.001	<.001	3	6
GBM	GATAD2B →	+0.352	+0.375	<.001	<.001	3	6
GBM	P4HB →	-0.405	-0.332	<.001	<.001	3	6
HNSC	TRRAP →	+0.251	+0.554	<.001	<.001	3	6
LUAD	RPRD2 →	+0.311	+0.428	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,085 associations by consensus.

NR2C2 vs TOP2B — GBM

Explore this scatter interactively →