NR2C2

Across TCGA cell cohorts, NR2C2 mutation is significantly associated with the RNA expression of many other genes, with 647 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NR2C2-associated genes across cancer lineages are MTRNR2L10, SSX7, and GJA10. Each is linked with NR2C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NR2C2-to-partner and partner-to-NR2C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L10 grouped by NR2C2-low versus NR2C2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2C2→partner) and Y-score (partner→NR2C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MTRNR2L10 →	+0.012	+5.357	<.001	.001	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
BLOOD_Leukemia	GJA10 →	+0.062	+4.705	<.001	.003	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.022	+4.539	<.001	.007	3	1
LARGE_INTESTINE	ANKRD54 →	+0.500	+3.714	.001	<.001	3	1
LARGE_INTESTINE	DEPDC5 →	+0.531	+3.459	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 647 associations by consensus.

MTRNR2L10 by NR2C2 expression — CNS

Explore this box plot interactively →