NR1H2

Across TCGA patient cohorts, NR1H2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,255 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NR1H2-associated proteins across cancer lineages are SRP72, TRIM28_S489, and PPP1R13L. Each is linked with NR1H2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NR1H2-to-partner and partner-to-NR1H2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR1H2 versus SRP72 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1H2→partner) and Y-score (partner→NR1H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRP72 →	-0.204	-0.330	<.001	<.001	3	4
PDAC	TRIM28_S489 →	+0.728	+0.199	.001	.007	3	3
OV	PPP1R13L →	+0.410	+0.480	.001	.001	2	4
OV	PMPCA →	-0.332	-0.455	<.001	.001	3	3
LSCC	CD109 →	+0.438	+0.270	.006	.008	3	3
PDAC	CHMP2A →	+0.376	+0.334	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,255 associations by consensus.

NR1H2 vs SRP72 — LSCC

Explore this scatter interactively →