NR1H2

Across TCGA cell cohorts, NR1H2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,681 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NR1H2-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Cytosolic transport, and Negative regulation of hyaluronan biosynthetic process. Each is linked with NR1H2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NR1H2-to-partner and partner-to-NR1H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by NR1H2-low versus NR1H2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1H2→partner) and Y-score (partner→NR1H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein-containing complex assembly →	+0.085	+1.033	<.001	<.001	3	15
BONE	Cytosolic transport →	+0.080	+0.979	.001	<.001	3	14
LIVER	Negative regulation of hyaluronan biosynthetic process →	+0.197	+1.042	.002	.004	3	14
LARGE_INTESTINE	Retrograde transport, endosome to Golgi →	+0.072	+0.724	<.001	.004	3	14
CNS	Asparaginyl-tRNA aminoacylation →	-0.140	-0.897	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of autophagy →	+0.073	+0.781	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,681 associations by consensus.

Negative regulation of protein-containing complex assembly by NR1H2 expression — BONE

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