NR1D2

Across TCGA cell cohorts, NR1D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,437 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NR1D2-associated GO terms across cancer lineages are Amyloid-beta clearance by transcytosis, Negative regulation of organelle assembly, and Regulation of cell cycle G1/S phase transition. Each is linked with NR1D2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NR1D2-to-partner and partner-to-NR1D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amyloid-beta clearance by transcytosis grouped by NR1D2-low versus NR1D2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1D2→partner) and Y-score (partner→NR1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Amyloid-beta clearance by transcytosis →	+0.209	+1.897	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of organelle assembly →	+0.056	+0.584	<.001	.004	3	14
STOMACH	Regulation of cell cycle G1/S phase transition →	+0.064	+1.162	.001	<.001	3	13
SKIN	Regulation of G1/S transition of mitotic cell cycle →	+0.068	+0.871	<.001	<.001	3	13
STOMACH	Regulation of post-translational protein modification →	+0.073	+1.358	.001	<.001	3	13
KIDNEY	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.064	+1.026	.003	.005	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,437 associations by consensus.

Amyloid-beta clearance by transcytosis by NR1D2 expression — BONE

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