NR0B2

Across TCGA cell cohorts, NR0B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,393 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NR0B2-associated GO terms across cancer lineages are Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, Negative regulation of epithelial to mesenchymal transition, and Negative regulation of dendritic cell differentiation. Each is linked with NR0B2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NR0B2-to-partner and partner-to-NR0B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway grouped by NR0B2-low versus NR0B2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR0B2→partner) and Y-score (partner→NR0B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway →	-0.099	-0.055	.006	.001	3	5
LIVER	Negative regulation of epithelial to mesenchymal transition →	+0.117	+3.410	.002	<.001	3	5
LUNG_SCLC	Negative regulation of dendritic cell differentiation →	+1.408	+2.513	<.001	<.001	3	5
LUNG_SCLC	Serotonin biosynthetic process →	+1.884	+3.452	<.001	<.001	3	5
LUNG_SCLC	Indole-containing compound biosynthetic process →	+1.982	+3.522	<.001	<.001	3	5
BLOOD_Myeloma	Aorta development →	-0.071	-0.055	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,393 associations by consensus.

Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway by NR0B2 expression — BLOOD_Lymphoma

Explore this box plot interactively →