NR0B1

Across TCGA patient cohorts, NR0B1 mutation is significantly associated with the RNA expression of many other genes, with 3,114 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR0B1-associated genes across cancer lineages are RNA5SP248, C1QBP, and MND1. Each is linked with NR0B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NR0B1-to-partner and partner-to-NR0B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP248 grouped by NR0B1-low versus NR0B1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR0B1→partner) and Y-score (partner→NR0B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP248 →	+0.442	+3.071	<.001	.003	3	4
UCEC	C1QBP →	+0.534	+3.043	<.001	<.001	3	3
UCEC	MND1 →	+0.736	+3.638	<.001	.001	3	3
COAD	EMC1 →	+0.489	+3.154	<.001	<.001	3	3
UCEC	ZIC5 →	+1.049	+2.024	<.001	<.001	3	3
UCEC	RPS27L →	+0.525	+2.343	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,114 associations by consensus.

RNA5SP248 by NR0B1 expression — STAD

Explore this box plot interactively →