NPY4R2

Across TCGA patient cohorts, NPY4R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,975 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPY4R2-associated GO terms across cancer lineages are Positive regulation of stress-activated protein kinase signaling cascade, Positive regulation of JNK cascade, and Tissue homeostasis. Each is linked with NPY4R2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NPY4R2-to-partner and partner-to-NPY4R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress-activated protein kinase signaling cascade grouped by NPY4R2-low versus NPY4R2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY4R2→partner) and Y-score (partner→NPY4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of stress-activated protein kinase signaling cascade →	+0.033	+0.241	<.001	<.001	3	15
STAD	Positive regulation of JNK cascade →	+0.044	+0.333	<.001	<.001	3	14
ESCA	Tissue homeostasis →	+0.033	+0.306	<.001	<.001	3	14
STAD	Cellular response to oxidative stress →	+0.040	+0.224	<.001	<.001	3	14
TGCT	Establishment of Golgi localization →	+0.072	+0.055	<.001	.001	3	14
STAD	Cellular response to light stimulus →	+0.032	+0.217	.002	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,975 associations by consensus.

Positive regulation of stress-activated protein kinase signaling cascade by NPY4R2 expression — STAD

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