NPY1R

Across TCGA pan-cancer cohorts, NPY1R Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NPY1R data layer compared with 22 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NPY1R Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated NPY1R expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, ACC, and PRAD are the cancer types where NPY1R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.890	.012	36	view →
ACC	OS	Median	All	0.273	0.802	.017	15	view →
PRAD	DFS	Median	All	0.617	0.886	.041	6	view →
LIHC	OS	Median	All	0.144	0.704	.016	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NPY1R–UCEC (DFS)

Open the UCEC breakdown →