NPY1R

Across TCGA cell cohorts, NPY1R RNA expression is significantly associated with the go_rna of many other GO terms, with 2,959 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPY1R-associated GO terms across cancer lineages are Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, Potassium ion transmembrane transport, and Cytoplasmic translation. Each is linked with NPY1R in more than 8 cancer types. Because this analysis shows association rather than direction, both NPY1R-to-partner and partner-to-NPY1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway grouped by NPY1R-low versus NPY1R-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY1R→partner) and Y-score (partner→NPY1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.053	-1.146	.007	.004	3	9
LARGE_INTESTINE	Potassium ion transmembrane transport →	-0.030	-0.465	<.001	.007	3	8
STOMACH	Cytoplasmic translation →	+0.100	+0.666	.002	.009	2	8
OVARY	Alternative mRNA splicing, via spliceosome →	+0.077	+0.372	.008	.006	1	9
PANCREAS	Cardiac muscle cell contraction →	-0.087	-0.375	<.001	.009	3	7
BONE	mRNA 3'-end processing →	+0.126	+3.693	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,959 associations by consensus.

Adenylate cyclase-modulating G protein-coupled receptor signaling pathway by NPY1R expression — KIDNEY

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