Across TCGA pan-cancer cohorts, NPW Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NPW data layer compared with 25 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher NPW Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NPW expression acts as an unfavorable survival marker.

ESCA and CHOL are the cancer types where NPW Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NPW tumor-vs-normal RNA expression · all NPW data types