Across TCGA cell cohorts, NPW mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NPW-associated genes across cancer lineages are HTR3D, FABP12, and OR6Y1. Each is linked with NPW in more than 1 cancer types. Because this analysis shows association rather than direction, both NPW-to-partner and partner-to-NPW results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPW→partner) and Y-score (partner→NPW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HTR3D →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	FABP12 →	+0.106	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR6Y1 →	+0.013	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NPW survival (RNA) · tumor vs normal (RNA) · all NPW data types