NPVF

Across TCGA patient cohorts, NPVF protein abundance is significantly associated with the RNA expression of many other genes, with 4,521 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NPVF-associated genes across cancer lineages are ASPA, FHL5, and DNAH7. Each is linked with NPVF in more than 2 cancer types. Because this analysis shows association rather than direction, both NPVF-to-partner and partner-to-NPVF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPVF versus ASPA in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPVF→partner) and Y-score (partner→NPVF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASPA →	+0.861	+1.741	.004	.007	3	3
BRCA	FHL5 →	+0.860	+1.259	.001	.008	3	3
BRCA	DNAH7 →	+0.650	+1.728	<.001	<.001	3	3
BRCA	TEK →	+0.789	+1.422	.001	.002	3	3
LUAD	MYCT1 →	+0.678	+0.607	<.001	<.001	3	3
BRCA	TEKT3 →	+0.934	+1.536	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,521 associations by consensus.

NPVF vs ASPA — BRCA

Explore this scatter interactively →