Across TCGA cell cohorts, NPVF RNA expression is significantly associated with the mutation status of many other genes, with 118 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NPVF-associated genes across cancer lineages are FOXK1, TCHH, and KLHL2. Each is linked with NPVF in more than 3 cancer types. Because this analysis shows association rather than direction, both NPVF-to-partner and partner-to-NPVF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPVF→partner) and Y-score (partner→NPVF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	FOXK1 →	+5.000	+0.020	.005	<.001	3	4
BONE	TCHH →	+4.672	+0.053	.001	<.001	3	2
LUNG_NSCLC_LUAD	KLHL2 →	+5.662	+0.029	.002	<.001	3	2
LUNG_NSCLC_LUAD	MUC4 →	+2.440	+0.007	.008	.001	3	2
LUNG_NSCLC_LUAD	GSAP →	+4.662	+0.014	.005	<.001	3	2
SOFT_TISSUE	ECE1 →	+4.930	+0.012	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 118 associations by consensus.

Exploration

NPVF survival (RNA) · tumor vs normal (RNA) · all NPVF data types