NPTN

Across TCGA patient cohorts, NPTN RNA expression is significantly associated with the protein abundance of many other proteins, with 14,243 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NPTN-associated proteins across cancer lineages are PKM, UBR1, and LPP. Each is linked with NPTN in more than 6 cancer types. Because this analysis shows association rather than direction, both NPTN-to-partner and partner-to-NPTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPTN versus PKM in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTN→partner) and Y-score (partner→NPTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PKM →	+0.482	+0.391	<.001	<.001	3	7
BRCA	UBR1 →	+0.229	+0.532	<.001	.006	3	7
UCEC	LPP →	+0.699	+0.317	<.001	.001	3	6
CCRCC	PDLIM5 →	+0.726	+0.251	<.001	<.001	3	6
COAD	PTPN9 →	+0.278	+0.442	<.001	.001	3	6
BRCA	TIMP2 →	+0.604	+0.704	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,243 associations by consensus.

NPTN vs PKM — PDAC

Explore this scatter interactively →