NPR3

Across TCGA patient cohorts, NPR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,689 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NPR3-associated proteins across cancer lineages are SEPTIN11, PLCD1, and ARHGEF17. Each is linked with NPR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both NPR3-to-partner and partner-to-NPR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPR3 versus SEPTIN11 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPR3→partner) and Y-score (partner→NPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN11 →	+0.326	+0.876	<.001	<.001	3	7
LUAD	PLCD1 →	+0.379	+0.896	<.001	<.001	3	6
COAD	ARHGEF17 →	+0.480	+1.014	<.001	<.001	3	6
PDAC	ARHGEF17_S1331 →	+0.614	+1.312	<.001	<.001	3	6
UCEC	RAB23 →	+0.515	+1.006	<.001	<.001	3	5
PDAC	INTS9_S572 →	-0.387	-1.089	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,689 associations by consensus.

NPR3 vs SEPTIN11 — BRCA

Explore this scatter interactively →