NPR1

Across TCGA patient cohorts, NPR1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,584 significant associations in total. OV shows the largest number of these associations.

The most reproducible NPR1-associated genes across cancer lineages are TMEM9, RNU6-621P, and NEIL3. Each is linked with NPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPR1-to-partner and partner-to-NPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPR1 versus TMEM9 in UCEC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPR1→partner) and Y-score (partner→NPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM9 →	-1.515	-0.650	.003	.008	3	2
UCEC	RNU6-621P →	-1.465	-0.564	.001	.008	3	2
LUAD	NEIL3 →	-1.024	-0.569	.006	.001	3	2
LUAD	CLIC5 →	+1.199	+0.544	<.001	.009	3	2
LUAD	CDC25A →	-0.841	-0.498	.007	.004	3	2
LUAD	JPT1 →	-0.721	-0.558	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,584 associations by consensus.

NPR1 vs TMEM9 — UCEC

Explore this scatter interactively →