NPPA

Across TCGA patient cohorts, NPPA RNA expression is significantly associated with the go_rna of many other GO terms, with 7,129 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible NPPA-associated GO terms across cancer lineages are Peptidyl-lysine modification, Nucleobase-containing compound transport, and Peptidyl-lysine acetylation. Each is linked with NPPA in more than 25 cancer types. Because this analysis shows association rather than direction, both NPPA-to-partner and partner-to-NPPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by NPPA-low versus NPPA-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPPA→partner) and Y-score (partner→NPPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Peptidyl-lysine modification →	+0.059	+0.421	.003	<.001	3	26
STAD	Nucleobase-containing compound transport →	+0.059	+0.235	<.001	<.001	3	25
STAD	Peptidyl-lysine acetylation →	+0.062	+0.242	<.001	<.001	3	25
STAD	Spliceosomal complex assembly →	+0.063	+0.303	<.001	<.001	3	25
STAD	Obsolete regulation of histone modification →	+0.057	+0.223	<.001	<.001	3	25
STAD	Macromolecule methylation →	+0.054	+0.261	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,129 associations by consensus.

Peptidyl-lysine modification by NPPA expression — ESCA

Explore this box plot interactively →