NPNT

Across TCGA cell cohorts, NPNT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,303 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPNT-associated GO terms across cancer lineages are Adenylate cyclase-activating serotonin receptor signaling pathway, Negative regulation of mRNA catabolic process, and Protein transport into membrane raft. Each is linked with NPNT in more than 9 cancer types. Because this analysis shows association rather than direction, both NPNT-to-partner and partner-to-NPNT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-activating serotonin receptor signaling pathway grouped by NPNT-low versus NPNT-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPNT→partner) and Y-score (partner→NPNT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Adenylate cyclase-activating serotonin receptor signaling pathway →	+0.204	+2.939	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of mRNA catabolic process →	+0.077	+2.291	<.001	<.001	3	9
SKIN	Protein transport into membrane raft →	+0.811	+1.092	<.001	.008	3	9
LUNG_NSCLC_LUAD	Neutrophil extravasation →	-0.418	-2.466	.001	<.001	3	8
LUNG_NSCLC_LUSC	Positive regulation of establishment of T cell polarity →	-0.257	-2.967	.001	.001	3	8
LUNG_NSCLC_LUSC	Dentinogenesis →	-1.506	-2.375	.002	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,303 associations by consensus.

Adenylate cyclase-activating serotonin receptor signaling pathway by NPNT expression — OVARY

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