NPM1P52

Across TCGA pan-cancer cohorts, NPM1P52 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NPM1P52’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NPM1P52 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P52 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

COAD, BRCA, and THCA are the cancer types where NPM1P52 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P52 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	+0.083	.026	4	view →
BRCA	All	IV	−0.130	.005	2	view →
THCA	All	All	−0.028	.018	2	view →
LUAD	Male	III,IV	+0.071	.049	1	view →
LUSC	Female	All	+0.032	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NPM1P52–COAD

Open the COAD breakdown →