NPM1P45

Across TCGA patient cohorts, NPM1P45 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,086 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NPM1P45-associated proteins across cancer lineages are PGRMC1_S181, CCDC102A, and CDK5. Each is linked with NPM1P45 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPM1P45-to-partner and partner-to-NPM1P45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPM1P45 versus PGRMC1_S181 in OV, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPM1P45→partner) and Y-score (partner→NPM1P45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PGRMC1_S181 →	+0.823	+0.047	.003	.005	3	2
GBM	CCDC102A →	-0.229	-0.136	.003	.003	3	2
CCRCC	CDK5 →	+0.214	+0.103	.001	.002	3	2
GBM	RPL22L1 →	-0.599	-0.138	<.001	.004	3	2
UCEC	SRRM2_S2382 →	+0.280	+0.082	.004	.007	3	2
OV	MPRIP_S993 →	-0.878	-0.052	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,086 associations by consensus.

NPM1P45 vs PGRMC1_S181 — OV

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