Across TCGA pan-cancer cohorts, NPM1P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NPM1P4’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NPM1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P4 is over-expressed in tumor.

HNSC and LIHC are the cancer types where NPM1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.044	.020	4	view →
LIHC	All	II,III,IV	+0.020	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NPM1P4 RNA expression & survival · all NPM1P4 data types