Across TCGA pan-cancer cohorts, NPM1P38 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of NPM1P38’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NPM1P38 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P38 is over-expressed in tumor.
HNSC, LUAD, and LUSC are the cancer types where NPM1P38 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P38 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.