NPM1P35

Across TCGA pan-cancer cohorts, NPM1P35 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated NPM1P35 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher NPM1P35 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NPM1P35 expression acts as an unfavorable survival marker, although some lineages such as READ and KIRC show a favorable association.

READ, KIRC, and CHOL are the cancer types where NPM1P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.741	0.418	<.001	106	view →
KIRC	OS	Median	All	0.905	0.842	.001	55	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	51	view →
THYM	DFS	Tertile	III,IV	1.000	0.212	.002	40	view →
ACC	OS	Tertile	All	0.272	0.709	<.001	37	view →
HNSC	OS	Quartile	IV	0.300	0.676	.006	26	view →
SKCM	OS	Tertile	All	0.898	0.845	.008	18	view →
MESO	OS	Median	All	0.755	0.271	<.001	18	view →
KIRP	DFS	Median	III,IV	0.578	0.827	.017	16	view →
CESC	OS	Tertile	II,III,IV	0.853	0.633	.014	16	view →
LUSC	DFS	Quartile	III,IV	0.155	0.784	.002	16	view →
LIHC	OS	Quartile	II,III,IV	0.186	0.502	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

NPM1P35–READ (DFS)

Open the READ breakdown →