NPM1P34

Across TCGA pan-cancer cohorts, NPM1P34 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NPM1P34 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher NPM1P34 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NPM1P34 expression acts as an unfavorable survival marker, although some lineages such as THCA and SKCM show a favorable association.

THCA, SKCM, and UCS are the cancer types where NPM1P34 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	III,IV	0.982	0.666	<.001	47	view →
SKCM	OS	Median	All	0.836	0.731	<.001	33	view →
UCS	DFS	Tertile	IV	0.793	0.239	.024	30	view →
LUAD	OS	Quartile	All	0.220	0.471	.008	30	view →
PCPG	OS	Tertile	All	0.804	1.000	.006	19	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
COAD	OS	Median	IV	0.321	0.777	.005	18	view →
UVM	DFS	Quartile	III,IV	0.204	0.611	.010	17	view →
READ	OS	Tertile	IV	0.628	1.000	.008	15	view →
ACC	DFS	Tertile	All	0.255	0.550	.004	13	view →
KIRP	OS	Tertile	All	0.599	0.852	.005	10	view →
GBM	DFS	Tertile	All	0.347	0.206	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

NPM1P34–THCA (OS)

Open the THCA breakdown →