Across TCGA pan-cancer cohorts, NPM1P30 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NPM1P30’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NPM1P30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P30 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, UCEC, and LUSC are the cancer types where NPM1P30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+0.075	.021	4	view →
UCEC	All	All	+0.183	.017	2	view →
LUSC	Male	III,IV	+0.117	.025	2	view →
THCA	Female	All	−0.069	.010	2	view →
HNSC	Male	All	+0.028	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: NPM1P30 RNA expression & survival · all NPM1P30 data types