NPM1P3

Across TCGA pan-cancer cohorts, NPM1P3 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NPM1P3 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher NPM1P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NPM1P3 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

READ, UCEC, and UCS are the cancer types where NPM1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	All	0.756	0.376	<.001	51	view →
UCEC	OS	Quartile	All	0.528	0.773	.001	48	view →
UCS	OS	Tertile	IV	0.898	0.359	.024	30	view →
STAD	DFS	Tertile	All	0.553	0.787	.008	24	view →
KIRP	DFS	Median	III,IV	0.772	0.471	.006	17	view →
DLBC	DFS	Median	All	0.629	1.000	.017	9	view →
ESCA	OS	Median	All	0.405	0.576	.038	8	view →
HNSC	OS	Median	All	0.253	0.468	.015	8	view →
SKCM	DFS	Tertile	IV	0.059	0.513	.018	7	view →
THYM	OS	Quartile	III,IV	0.615	1.000	.033	6	view →
COAD	OS	Quartile	All	0.857	0.531	.013	4	view →
PRAD	OS	Median	All	1.000	0.979	.027	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NPM1P3–READ (DFS)

Open the READ breakdown →