NPM1P26

Across TCGA pan-cancer cohorts, NPM1P26 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated NPM1P26 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NPM1P26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P26 expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.

UCEC, UCS, and SARC are the cancer types where NPM1P26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.789	0.908	.001	102	view →
UCS	OS	Tertile	IV	0.844	0.241	.024	30	view →
SARC	DFS	Median	All	0.447	0.722	<.001	21	view →
LAML	DFS	Quartile	All	0.579	0.232	.005	20	view →
READ	DFS	Median	IV	0.347	0.841	.001	18	view →
KIRP	DFS	Quartile	All	0.637	0.845	.003	13	view →
LIHC	OS	Quartile	All	0.971	0.757	.005	11	view →
ACC	DFS	Quartile	All	0.272	0.645	.006	6	view →
CESC	DFS	Median	All	0.685	0.787	.033	6	view →
SKCM	DFS	Quartile	All	0.263	0.124	.009	5	view →
ESCA	OS	Median	II,III,IV	0.617	1.000	.049	3	view →
LUSC	OS	Median	IV	0.851	0.255	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

NPM1P26–UCEC (OS)

Open the UCEC breakdown →