NPM1P22

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NPM1P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,192 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPM1P22-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Ribosome disassembly, and Ribosomal small subunit biogenesis. Each is linked with NPM1P22 in more than 23 cancer types. Because this analysis shows association rather than direction, both NPM1P22-to-partner and partner-to-NPM1P22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPM1P22→partner) and Y-score (partner→NPM1P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAMaturation of SSU-rRNA →+0.058+0.130.002.001324
STADRibosome disassembly →+0.041+0.149<.001<.001322
ESCARibosomal small subunit biogenesis →+0.059+0.133.005.002223
ESCAMaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.070+0.198.003<.001322
ESCARibosomal large subunit biogenesis →+0.066+0.163.008.001222
STADTranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →+0.044+0.138<.001<.001321
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,192 associations by consensus.

Exploration