NPM1P17

Across TCGA patient cohorts, NPM1P17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,371 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPM1P17-associated GO terms across cancer lineages are scaRNA localization to Cajal body, Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Maturation of LSU-rRNA. Each is linked with NPM1P17 in more than 6 cancer types. Because this analysis shows association rather than direction, both NPM1P17-to-partner and partner-to-NPM1P17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, scaRNA localization to Cajal body grouped by NPM1P17-low versus NPM1P17-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPM1P17→partner) and Y-score (partner→NPM1P17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	scaRNA localization to Cajal body →	+0.035	+0.044	<.001	.005	3	7
UCEC	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.050	+0.025	<.001	<.001	3	7
UCEC	Maturation of LSU-rRNA →	+0.048	+0.024	<.001	<.001	3	7
UCEC	Response to misfolded protein →	+0.045	+0.026	<.001	<.001	3	7
UCEC	Mitotic DNA replication →	+0.059	+0.032	<.001	<.001	3	6
UCEC	Rhythmic process →	+0.030	+0.051	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,371 associations by consensus.

scaRNA localization to Cajal body by NPM1P17 expression — COAD

Explore this box plot interactively →