Across TCGA pan-cancer cohorts, NPM1P14 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of NPM1P14’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NPM1P14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P14 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.
LUSC, KIRC, and LUAD are the cancer types where NPM1P14 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P14 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.