NPM1P13

Across TCGA pan-cancer cohorts, NPM1P13 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated NPM1P13 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher NPM1P13 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P13 expression acts as an unfavorable survival marker, although some lineages such as ACC and LUSC show a favorable association.

DLBC, UVM, and HNSC are the cancer types where NPM1P13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.386	0.826	.001	48	view →
UVM	OS	Tertile	II,III,IV	0.458	0.731	.005	45	view →
HNSC	OS	Tertile	IV	0.425	0.726	.003	28	view →
LGG	DFS	Tertile	All	0.694	0.844	.001	27	view →
ACC	DFS	Tertile	IV	0.667	0.165	.013	18	view →
LUSC	OS	Quartile	All	0.784	0.375	<.001	18	view →
READ	OS	Tertile	All	0.545	0.837	.046	9	view →
ESCA	OS	Quartile	III,IV	0.767	0.322	.022	6	view →
OV	DFS	Quartile	All	0.477	0.553	.045	4	view →
SARC	OS	Median	All	0.771	0.869	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

NPM1P13–DLBC (OS)

Open the DLBC breakdown →