NPLP1

Across TCGA pan-cancer cohorts, NPLP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NPLP1’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where NPLP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPLP1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

PRAD and LUSC are the cancer types where NPLP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPLP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.051	.022	2	view →
LUSC	Male	II,III,IV	−0.033	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

NPLP1–PRAD

Open the PRAD breakdown →