NPLOC4

Across TCGA cell cohorts, NPLOC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,529 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NPLOC4-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of RIG-I signaling pathway, and Retrograde transport, endosome to Golgi. Each is linked with NPLOC4 in more than 14 cancer types. Because this analysis shows association rather than direction, both NPLOC4-to-partner and partner-to-NPLOC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by NPLOC4-low versus NPLOC4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPLOC4→partner) and Y-score (partner→NPLOC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.095	+1.080	<.001	.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of RIG-I signaling pathway →	+0.195	+0.888	<.001	.003	3	15
LARGE_INTESTINE	Retrograde transport, endosome to Golgi →	+0.062	+0.900	<.001	<.001	3	15
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.068	+0.709	<.001	<.001	3	15
STOMACH	Macroautophagy →	+0.066	+0.670	.004	.004	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.075	+1.160	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,529 associations by consensus.

Cytosolic transport by NPLOC4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →