NPIPB8

Across TCGA patient cohorts, NPIPB8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,881 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPIPB8-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Macromolecule methylation, and Obsolete histone H3-K4 methylation. Each is linked with NPIPB8 in more than 27 cancer types. Because this analysis shows association rather than direction, both NPIPB8-to-partner and partner-to-NPIPB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by NPIPB8-low versus NPIPB8-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB8→partner) and Y-score (partner→NPIPB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Epigenetic regulation of gene expression →	+0.070	+0.072	<.001	.001	3	28
STAD	Macromolecule methylation →	+0.054	+0.084	<.001	<.001	3	28
DLBC	Obsolete histone H3-K4 methylation →	+0.075	+0.072	.001	.001	3	27
STAD	Regulation of post-translational protein modification →	+0.059	+0.079	<.001	<.001	3	27
STAD	Regulation of stem cell differentiation →	+0.059	+0.072	<.001	<.001	3	27
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.072	+0.099	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,881 associations by consensus.

Epigenetic regulation of gene expression by NPIPB8 expression — DLBC

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