NPIPB5

Across TCGA patient cohorts, NPIPB5 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NPIPB5-associated genes across cancer lineages are MOS, TSPY13P, and DAZ1. Each is linked with NPIPB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPIPB5-to-partner and partner-to-NPIPB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOS grouped by NPIPB5-low versus NPIPB5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB5→partner) and Y-score (partner→NPIPB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MOS →	+0.043	+5.721	.001	.003	3	1
BRCA	TSPY13P →	+0.019	+8.057	<.001	.005	3	1
BRCA	DAZ1 →	+0.003	+7.471	<.001	.008	3	1
BRCA	RNU6-1123P →	+0.331	+5.175	.001	.007	3	1
BRCA	RNA5SP487 →	+0.188	+7.471	<.001	.008	3	1
UCEC	RN7SL134P →	+0.222	+3.599	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

MOS by NPIPB5 expression — BRCA

Explore this box plot interactively →