NPIPB5

Across TCGA cell cohorts, NPIPB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,717 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPIPB5-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with NPIPB5 in more than 15 cancer types. Because this analysis shows association rather than direction, both NPIPB5-to-partner and partner-to-NPIPB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by NPIPB5-low versus NPIPB5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB5→partner) and Y-score (partner→NPIPB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.221	+1.537	<.001	<.001	3	16
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.164	+1.533	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.109	+1.417	<.001	<.001	3	15
KIDNEY	Chiasma assembly →	+0.358	+1.565	<.001	<.001	3	15
SOFT_TISSUE	Microtubule nucleation →	+0.129	+1.926	<.001	<.001	3	14
SOFT_TISSUE	Regulation of double-strand break repair →	+0.080	+1.729	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,717 associations by consensus.

Pre-mRNA catabolic process by NPIPB5 expression — BONE

Explore this box plot interactively →