NPIPB2

Across TCGA patient cohorts, NPIPB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,598 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPIPB2-associated GO terms across cancer lineages are Nucleotide-excision repair, Macromolecule methylation, and Protein localization to cilium. Each is linked with NPIPB2 in more than 18 cancer types. Because this analysis shows association rather than direction, both NPIPB2-to-partner and partner-to-NPIPB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by NPIPB2-low versus NPIPB2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB2→partner) and Y-score (partner→NPIPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nucleotide-excision repair →	+0.047	+0.325	<.001	.002	2	19
ESCA	Macromolecule methylation →	+0.054	+0.386	<.001	<.001	3	17
ESCA	Protein localization to cilium →	+0.032	+0.375	<.001	<.001	3	17
STAD	tRNA metabolic process →	+0.043	+0.319	<.001	<.001	3	17
ESCA	Microtubule-based transport →	+0.042	+0.439	<.001	<.001	3	16
STAD	Obsolete ncRNA export from nucleus →	+0.046	+0.183	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,598 associations by consensus.

Nucleotide-excision repair by NPIPB2 expression — ESCA

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