Across TCGA pan-cancer cohorts, NPIPB13 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of NPIPB13’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where NPIPB13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPIPB13 is over-expressed in tumor.
STAD, KIRC, and KIRP are the cancer types where NPIPB13 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPIPB13 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.