NPIPB11

Across TCGA cell cohorts, NPIPB11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,159 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NPIPB11-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, mRNA 5'-splice site recognition, and Chiasma assembly. Each is linked with NPIPB11 in more than 13 cancer types. Because this analysis shows association rather than direction, both NPIPB11-to-partner and partner-to-NPIPB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by NPIPB11-low versus NPIPB11-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPIPB11→partner) and Y-score (partner→NPIPB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.141	+0.752	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA 5'-splice site recognition →	+0.134	+0.615	<.001	<.001	3	14
BONE	Chiasma assembly →	+0.372	+0.564	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.203	+0.739	<.001	<.001	3	13
OVARY	Regulation of alternative mRNA splicing, via spliceosome →	+0.089	+0.467	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+1.608	+0.790	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,159 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by NPIPB11 expression — KIDNEY

Explore this box plot interactively →